Educational Background: RC, after her degree in Physics at the University of Bologna, Italy, attended several courses both in Italy and abroad and acquired experience and theoretical background in different fields, such as Computer Science, Membrane and Protein Biophysics, Bioenergetics and Irreversible Thermodynamics.

Professional Experience: After working in Laboratories of Biophysics both in the United States and in Germany, in 1987 RC became Assistant Professor of Biophysics at the University of Bologna Italy and in 1/10/2003 full professor of Biochemistry. Since 1-11-20019 she is Alma Mater Professor. As to her research, RC worked in membrane and protein Biophysics (particularly with bacteriorhodopsin from Halobacterium Halobium and F1F0 ATPases from mesophilic organisms), both experimentally and theoretically. After establishing in 1995 the Biocomputing Group at the University of Bologna, she become active in computational modelling of relevant biological processes, such as protein folding, protein-protein interaction, genome annotation, protein interaction networks, SNPs search, annotation and disease association, and their effect on protein stability. One major field of research is the development of specific software for problem solving of large-scale analysis of biomedical and biotechnological data out of genome sequencing or experiments on proteomes and interactomes. Methods are based on shallow and deep neural networks, hidden Markov models, Support Vector Machines, conditional random fields and their combinations, and more recently embedding and transformer implementations. RC is the author of over 300 scientific papers and presented her work at several (over 300) national and international meetings (for details see http://www.biocomp.unibo.it/casadio).

Honors
In 2020 RC got the Distinctive honor of FELLOW from The International Society for Computational Biology (ISCB Fellow) in recognition of significance contributions and service to the field of computational biology.

Other activities
Since 2017-ongoing RC is Representative of the Italian Ministry of Education, University and Research in the European ELIXIR Board (www.Elixir-Europe.org), the largest European Bioinformatics infrastructure.
RC is Editor of Journal of Molecular Biology, of NAR Bioinformatics and Genomics and BMC Bioinformatics.