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General information about the entry
Entry name ADH_ZINC
Accession number PS00059
Entry type PATTERN
Date APR-1990 (CREATED); NOV-1997 (DATA UPDATE); JUL-1998 (INFO UPDATE).
PROSITE documentation PDOC00058
Name and characterization of the entry
Description Zinc-containing alcohol dehydrogenases signature.
Pattern G-H-E-x(2)-G-x(5)-[GA]-x(2)-[IVSAC].
Numerical results
  • Swiss-Prot release number: 40.7, total number of sequence entries in that release: 103373.
  • Total number of hits in Swiss-Prot: 186 hits in 186 different sequences
  • Number of hits on proteins that are known to belong to the set under consideration: 176 hits in 176 different sequences
  • Number of hits on proteins that could potentially belong to the set under consideration: 0 hits in 0 different sequences
  • Number of false hits (on unrelated proteins): 10 hits in 10 different sequences
  • Number of known missed hits: 3
  • Number of partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences: 3
  • Precision (true hits / (true hits + false positives)): 94.62 %
  • Recall (true hits / (true hits + false negatives)): 98.32 %
Comments
  • Taxonomic range: Archaebacteria, Eukaryotes, Prokaryotes (Bacteria)
  • Maximum known number of repetitions of the pattern in a single protein: 1
  • `Interesting' site in the pattern: 2,zinc
Cross-references
Swiss-Prot True positive hits:
ADH1_ALLMI (P80222), ADH1_APTAU (P49645), ADH1_ARATH (P06525), 
ADH1_ASPFL (P41747), ADH1_BACST (P12311), ADH1_CAEEL (Q17334), 
ADH1_CANAL (P43067), ADH1_CHICK (P23991), ADH1_EMENI (P08843), 
ADH1_ENTHI (P35630), ADH1_HORVU (P05336), ADH1_KLULA (P20369), 
ADH1_KLUMA (Q07288), ADH1_MAIZE (P00333), ADH1_NAJNA (P80512), 
ADH1_NEUCR (Q9P6C8), ADH1_ORYSA (P20306), ADH1_PEA   (P12886), 
ADH1_PENAM (P14219), ADH1_PETHY (P25141), ADH1_PICST (O00097), 
ADH1_RABIT (Q03505), ADH1_RANPE (P22797), ADH1_SOLTU (P14673), 
ADH1_STRCA (P80338), ADH1_TRIRP (P13603), ADH1_YEAST (P00330), 
ADH1_ZYMMO (P20368), ADH2_BACST (P42327), ADH2_CAEEL (O45687), 
ADH2_CANAL (O94038), ADH2_EMENI (P54202), ADH2_HORVU (P10847), 
ADH2_KLULA (P49383), ADH2_KLUMA (Q9P4C2), ADH2_LYCES (P28032), 
ADH2_MAIZE (P04707), ADH2_ORYSA (P18332), ADH2_PERMA (P41681), 
ADH2_PICST (O13309), ADH2_SOLTU (P14674), ADH2_STRCA (P80468), 
ADH2_YEAST (P00331), ADH3_BACST (P42328), ADH3_COTJA (P19631), 
ADH3_ECOLI (P25437), ADH3_EMENI (P07754), ADH3_HAEIN (P44557), 
ADH3_HORVU (P10848), ADH3_KLULA (P49384), ADH3_PASPI (P39450), 
ADH3_SOLTU (P14675), ADH3_SYNY3 (P73138), ADH3_YEAST (P07246), 
ADH4_KLULA (P49385), ADH4_RANPE (O57380), ADH5_YEAST (P38113), 
ADH6_HUMAN (P28332), ADH7_HUMAN (P40394), ADH7_MOUSE (Q64437), 
ADH7_RAT   (P41682), ADH_ALCEU  (P14940), ADH_CLOBE  (P25984), 
ADH_FRAAN  (P17648), ADH_GADCA  (P26325), ADH_MACMU  (P28469), 
ADH_MALDO  (P48977), ADH_MYCPN  (P75214), ADH_MYCTU  (P31975), 
ADH_PAPHA  (P14139), ADH_SCHPO  (P00332), ADH_SULSO  (P39462), 
ADH_SULSR  (P50381), ADH_THEBR  (P14941), ADHA_GEOBU (Q64413), 
ADHA_GEOKN (Q64415), ADHA_HUMAN (P07327), ADHA_MOUSE (P00329), 
ADHA_PERMA (P41680), ADHA_RAT   (P06757), ADHA_RHIME (O31186), 
ADHA_UROHA (P25405), ADHB_HUMAN (P00325), ADHB_UROHA (P25406), 
ADHE_HORSE (P00327), ADHG_HUMAN (P00326), ADHH_GADMO (P81600), 
ADHI_RHOSH (P72324), ADHL_GADMO (P81601), ADHP_ECOLI (P39451), 
ADHP_HUMAN (P08319), ADHP_RABIT (O46649), ADHQ_RABIT (O46650), 
ADHS_HORSE (P00328), ADHX_ARATH (Q96533), ADHX_CAEEL (Q17335), 
ADHX_DROME (P46415), ADHX_HORSE (P19854), ADHX_HUMAN (P11766), 
ADHX_MAIZE (P93629), ADHX_MOUSE (P28474), ADHX_MYXGL (P80360), 
ADHX_OCTVU (P81431), ADHX_ORYSA (P93436), ADHX_PEA   (P80572), 
ADHX_RABIT (O19053), ADHX_RAT   (P12711), ADHX_SPAAU (P79896), 
ADHX_UROHA (P80467), CAD1_ARACO (P42495), CAD1_ARATH (P48523), 
CAD1_EUCGU (Q42726), CAD2_ARATH (O49482), CAD2_EUCGU (P31655), 
CAD2_PICAB (O82035), CAD4_TOBAC (P30359), CAD7_PICAB (Q08350), 
CAD9_TOBAC (P30360), CADH_EUCBO (P50746), CADH_EUCGL (O64969), 
CADH_LOLPR (O22380), CADH_MAIZE (O24562), CADH_MEDSA (P31656), 
CADH_PINRA (Q40976), CADH_PINTA (P41637), CADH_POPDE (P31657), 
CADH_SACOF (O82056), DHSO_BACHD (Q9Z9U1), DHSO_BACSU (Q06004), 
DHSO_BOMMO (Q02912), DHSO_HUMAN (Q00796), DHSO_MOUSE (Q64442), 
DHSO_RAT   (P27867), DHSO_SCHPO (P36624), DHSO_SHEEP (P07846), 
DHSO_YEAST (P35497), FADH_AMYME (P80094), FADH_CANMA (Q06099), 
FADH_METMR (P47734), FADH_PARDE (P45382), FADH_PICPA (O74685), 
FADH_PSEPU (P46154), FADH_YEAST (P32771), FAH1_SCHPO (P78870), 
FAH2_SCHPO (O74540), FDEH_PSEPU (P09347), GATD_ECOLI (P37190), 
MTD1_ARATH (Q02971), MTD1_STYHU (Q43137), MTD2_ARATH (Q02972), 
MTD3_STYHU (Q43138), MTD_APIGR  (Q38707), MTD_FRAAN  (Q9ZRF1), 
MTD_MEDSA  (O82515), MTD_MESCR  (P93257), MTD_PETCR  (P42754), 
MTDH_ARATH (P42734), RSPB_ECOLI (P38105), TDH_BACSU  (O31776), 
TDH_ECOLI  (P07913), TDH_RHIME  (Q52998), TDH_XANCP  (O34268), 
TERD_PSESP (P33010), XYL2_PICST (P22144), XYLB_PSEPU (P39849), 
YAG0_YEAST (P39714), YAG1_YEAST (P39713), YAHK_ECOLI (P75691), 
YBDR_ECOLI (P77316), YCZ5_YEAST (P25377), YDJJ_ECOLI (P77280), 
YDJL_ECOLI (P77539), YJGB_ECOLI (P27250), YJJN_ECOLI (P39400), 
YM97_YEAST (Q04894), YPHC_ECOLI (P77360)
False negative hits (sequences which belong to the set under consideration, but which have not been picked up by the pattern or profile):
IDND_ECOLI (P39346), Y053_HAEIN (Q57517), YCJQ_ECOLI (P76043)
`Potential' hits (partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences):
ADH1_ZEALU (Q07264), ADH_ANAPL  (P30350), XYLB_ACIGB (P46364)
False positive hits (sequences which do not belong to the set under consideration):
DCDA_DEIRA (Q9RTK2), DHP1_SCHPO (P40848), GAL1_STRLI (P13227), 
GLNA_CHICK (P16580), IF2C_ARATH (Q9SHI1), IF2C_PHAVU (P57997), 
ISCS_METTE (P57795), LMG1_DROME (P15215), PAPC_ECOLI (P07110), 
THIM_PYRHO (O58877)
Retrieve an alignment of Swiss-Prot true positive hits:

[Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format]

PDB
[Detailed view]
1AGN; 1KEV; 1PED; 1CDO; 1YKF; 1DEH; 1HDX; 1HDY; 1HDZ; 1HTB; 3HUD; 1A71; 1A72; 1ADB; 1ADC; 1ADF; 1ADG; 1AXE; 1AXG; 1BTO; 1HLD; 1LDE; 1LDY; 2OHX; 2OXI; 3BTO; 5ADH; 6ADH; 7ADH; 8ADH; 1TEH; 1SDG;

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